Born at Pirano d’Istria near Trieste, Fragiacomo moved with his family to Venice, where he enrolled at the Academy of Fine Arts in 1878 after a period as a worker in Treviso. He then abandoned his studies barely one year later to devote himself more freely to painting from life, often in the company of his friend the painter Giacomo Favretto. He won a bronze medal at the Universal Exhibition of 1889 in Paris and took part in the Munich International Exhibition of the same year, as well as later editions. Drawing inspiration from the Venetian lagoon and always characterised by a crepuscular sense of nature, his landscapes took on Symbolist overtones at the end of the century. He won the Prince Umberto Prize at the Milan Triennale of 1891 and was a regular participant from 1895 to 1922 at the Venice Biennale, which held a solo show of his work in 1910 and a posthumous retrospective in 1924.