Trained as a decorator, Minerbi moved to Florence in 1901 and then Genoa. He made his debut in Venice at the 10th Esposizione Internazionale della Città di Venezia in 1912 and worked in the studio of Adolph Wildt in Milan after World War I. He held his first solo show at the Galleria Pesaro, Milan, in 1919 and took part in the Esposizione Regionale di Ferrara of 1920 and the Primaverile Fiorentina of 1922. The 1920s and 1930s saw a large number of commissions, above all for religious works like the Motherhood relief for the Mangiagalli Clinic (1930) and the depiction of Our Lady of the Assumption for the church of Santa Maria delle Grazie (1940) in Milan. Gabriele D’Annunzio commissioned him in 1938 to create a funeral monument for his mother Luisa in the Vittoriale.